So how much dust and dander are we talking about here? Haha now I'm worried. I'll have my chicks indoors for at least 3 weeks until our run is complete outside. I've lined the entire floor with plastic (an empty back bedroom) and have the brooder on a large rectangular table. Will running air cleaners help you think?
I would not brood chicks in a room with carpet or upholstered furniture. The dust won't be noticeable until about the second week, when feather growth really takes off. You'll have dust, dander, quil sheaths, and bits of shed down everywhere. Spare bathrooms work great, lots of easy to wipe down surfaces. Another option is brooding in a garage, basement, or other unfinished space.