Securing the pen
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It's a lot easier to help make improvements when we know what your current set up is.
Assuming the predators attacked during the day, to make the coop AND run secure-
1)secure the base- trench down 1-2 feet with cement blocks or something similar OR lay 1/2" hardware mesh underneath the coop/run and screw into the foundation frame (4x4's, for example) OR add an 'apron' of two feet 1/2" hardware mesh screwed onto the coop base and fanned out and secured with 12" garden staples, and back filled with pavers or gravel.
2) secure the walls and roof of the run with more 1/2" hardware mesh screwed into the frame.
3)make sure your coop and the frame of the run are well built.
4) put snap latches on your coop door/egg access and run doors with carabiners through them.