- Dec 7, 2011
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I will only post about the first 3 classes because I don't believe 4 &5 are of much use. This is from the guinea forum yrs ago.
Class I anthelmintics
: Benzimidazoles and pro-
benzimidazoles. These drugs exert their action on the
intracellular polymerization of the tubulin molecules to
microtubules. As the cellular functions are disrupted, the
worms die. Examples of Class I compounds are
albendazole, thiabendazole, fenbendazole, parbendazole,
flubendazole, febantel, and thiophanate. Here is what to
buy to use this class, Valbazen, Panacur or Safeguard. I
buy the Safeguard 10% suspension from TSC (goat
wormer) and use 2.5cc/gallon of drinking water. This class
of anthelmintics is best for gapeworm; the other classes
don't work too well for gapeworm.
Class II anthelmintics
: Imidazothiazoles and
tetrahydropyrimidines. These drugs act on the
acetylcholine receptor in the neuromuscular system of the
worms causing a persistent depolarization of muscle cells
and a spastic paralysis of the worms, which are then
removed by gut motility. Examples of Class II drugs are
levamisole, pyrantel, and morantel. Here is what to buy to
use this class wormer. TSC sells Tramisol or Levamisole
in a powder. It is in a 20 oz. bottle that contains just a little
powder. You are supposed to fill the bottle with water and
then use the mixed concentrate to add to the drinking
water. The mixed solution is good for 3 months. I wouldn't
use that much concentrate in years. I use 1/4
teaspoon/gallon of drinking water for three days. The
actual dosage is supposed to be closer to 1/3 of a
teaspoon, but you can overdose your birds with this one.
You can overdose with them all, but this one can be very
dangerous.
Class III anthelmintics
: Avermectins and milbymicins.
The compounds act on the nervous system of the worms,
causing flaccid paralysis and removal by gut motility. Class
III consists of two distinct types of drugs, i.e. the erazines
and the avermectins (ivermectin, doramectin, moxidectin),
the latter having effects against some ectoparasites, e.g.
mange mites. Most people use the ivermectin from this
class. Many use the ivermectin injectable and put
5cc/gallon of water. I use Eqvalan,
which is the same
ingredient as the ivermectin injectable, but it is water-
soluble. Same dosage, 5cc/gallon of drinking water.
As you can see, not all wormers will kill all kinds of worms.
When giving wormers it is best to remove their water
supply about midday the day before you are going to give it
to them. The next day mix up the wormer and give it to
your birds (this works best for me). That way they are
thirsty and will get a good bit right off the bat.
If you are going to give orally make sure you do not drown
the bird.
Draw the wormer in the syringe and then draw
some water to mix with it I hold the bird between my legs facing outward. Open
the beak and with a syringe with a 3” piece of
aquarium air tubing on the
end of it stick it down the
throat on the right side of the trachea; then administer
dosage
Class I anthelmintics
: Benzimidazoles and pro-
benzimidazoles. These drugs exert their action on the
intracellular polymerization of the tubulin molecules to
microtubules. As the cellular functions are disrupted, the
worms die. Examples of Class I compounds are
albendazole, thiabendazole, fenbendazole, parbendazole,
flubendazole, febantel, and thiophanate. Here is what to
buy to use this class, Valbazen, Panacur or Safeguard. I
buy the Safeguard 10% suspension from TSC (goat
wormer) and use 2.5cc/gallon of drinking water. This class
of anthelmintics is best for gapeworm; the other classes
don't work too well for gapeworm.
Class II anthelmintics
: Imidazothiazoles and
tetrahydropyrimidines. These drugs act on the
acetylcholine receptor in the neuromuscular system of the
worms causing a persistent depolarization of muscle cells
and a spastic paralysis of the worms, which are then
removed by gut motility. Examples of Class II drugs are
levamisole, pyrantel, and morantel. Here is what to buy to
use this class wormer. TSC sells Tramisol or Levamisole
in a powder. It is in a 20 oz. bottle that contains just a little
powder. You are supposed to fill the bottle with water and
then use the mixed concentrate to add to the drinking
water. The mixed solution is good for 3 months. I wouldn't
use that much concentrate in years. I use 1/4
teaspoon/gallon of drinking water for three days. The
actual dosage is supposed to be closer to 1/3 of a
teaspoon, but you can overdose your birds with this one.
You can overdose with them all, but this one can be very
dangerous.
Class III anthelmintics
: Avermectins and milbymicins.
The compounds act on the nervous system of the worms,
causing flaccid paralysis and removal by gut motility. Class
III consists of two distinct types of drugs, i.e. the erazines
and the avermectins (ivermectin, doramectin, moxidectin),
the latter having effects against some ectoparasites, e.g.
mange mites. Most people use the ivermectin from this
class. Many use the ivermectin injectable and put
5cc/gallon of water. I use Eqvalan,
which is the same
ingredient as the ivermectin injectable, but it is water-
soluble. Same dosage, 5cc/gallon of drinking water.
As you can see, not all wormers will kill all kinds of worms.
When giving wormers it is best to remove their water
supply about midday the day before you are going to give it
to them. The next day mix up the wormer and give it to
your birds (this works best for me). That way they are
thirsty and will get a good bit right off the bat.
If you are going to give orally make sure you do not drown
the bird.
Draw the wormer in the syringe and then draw
some water to mix with it I hold the bird between my legs facing outward. Open
the beak and with a syringe with a 3” piece of
aquarium air tubing on the
end of it stick it down the
throat on the right side of the trachea; then administer
dosage
