From what I have seen posted about poultry protector, it does not kill mites but repells them. If you have a large infestation, one that will kill chicks at hatch, you will need something stronger.
Spinosad is Organic so either something like captain jacks dead bug juice or Elektor is a good choice.
As I previously said frontline and pyrythrin products have their place and high infestations can to be treated aggressively with these products.
Just sharing that we've used Poultry Protector as a prevention on coops and chickens and have not faced infestations of either mites or lice or even spiders - in fact we were surprised that the ants were immobilized and dead when I sprayed a broken egg in the nestbox so ants did not crawl over my hands while cleaning up the mess. Not really surprising since I've killed ants with a quick squirt of perfume once LOL! It amazed us how effective Poultry Protector was on a couple lice-infested juveniles that were shipped to us - poor girls! And PP was instantly effective but we continued using it for a couple more days on the birds with a week's followup just to be sure. God forbid mites. They are much more difficult to rid!
I'm an ounce of prevention to save a pound of cure kind of person which is why the gentle Manna Pro products have been good for me. I'm glad to see spinosad is being commercially used as I researched it a couple years back and it sounded like an excellent choice for heavier treatments. I'm glad to finally hear some feedback from people who've actually used it!