No. You want to encourage her to come out and eat. Otherwise, she may stay in the nest and poop on the eggs. What is your climate? Are you ok with having chicks in the winter? She'll do ok with babies, and some hens do brood in the winter. But, one thing you'll need to do is be sure none of the other birds go in her nest to lay. They may crowd in on top of her, or sneak in when she comes out to eat/drink/poop. It would be a good idea to mark all of her eggs and be sure she doesn't have too many to succesfully cover. you might also want to candle them at some point and remove any that are not developing, or not as developed. She'll wait a day or two after the majority of the chicks hatch, then leave the nest and any eggs left behind will be left to die.
I'm in central Texas. She's in a pretty big house but the other hens and roosters stay out all day except to lay their eggs. As far as I can tell they are leaving her alone and laying in other boxes. I put some food in the box next to her but it didn't look like she's eaten. Should I pick her up and make her eat a couple times a day or is once a day good enough?