I haven't disturbed it and don't plan to. I do have Wasps however and I spray those suckers. I've been stung once as they try to build nests just inside the coop doors. Also under the eaves on the house.
They are also the main predator of the black and brown widow spiders.
Organ-pipe mud daubers build their very distinctive and elegant tubes on vertical or horizontal faces of walls, cliffs, bridges, overhangs and shelter caves or other structures.
I believe I might have seen one or tow in my garden as I water. In this dry weather it's likely my garden may be the only place to find mud.
Adults of both sexes frequently drink flower nectar, but they stock their nests with spiders, which serve as food for their offspring
So they do pollinate I guess and that's good for my garden.