Here's my final report on a one year old BO hen who arrived with others a year ago with 10 others, all hatchery vaccinated. They were raised for 3 weeks in my spare room and tended to with gown and scrubbed hands. Then they went into a hutch with a wire floor on my patio for another 3 weeks. At 6 weeks they went into a pen in the area of the rest of the flock. The hen in question was the only one who Corid .
They have lived in an open pen since 6 weeks old.
PCR velogenic primer/probe set is mandated and samples will be sent to NVSL for confirmation and further analysis. This test was developed by USDA for surveillance and is validated in poultry and wild waterfowl.
Virology Specimen Test Name Buff Orpington Hen - AVIAN - Chicken - Orpington - Female - 1 Years Multiple Tissues - Fresh Tissue - 3 Send Out (V.SENDOUT) (Test Performed at TVMDL) 3/5/15: Marek's Disease Virus (PCR-MDV-PCR): Positive This positive result could be due to vaccination or infection.
Necropsy Interpretive Summary chickens are the most important natural host for Marek's disease virus, a highly cell-associated but readily transmitted alpha herpesvirus with lymphotropic properties of gamma herpesviruses. The disease is highly contagious and readily transmitted among chickens. The virus matures into a fully infective, enveloped form in the epithelium of the feather follicle, from which it is released into the environment. It may survive for months in poultry house litter or dust. Dust or dander from infected chickens is particularly effective in transmission. Once the virus is introduced into a chicken flock, regardless of vaccination status, infection spreads quickly from bird to bird. Infected chickens continue to be carriers for long periods and act as sources of infectious virus. Shedding of infectious virus can be reduced, but not prevented, by prior vaccination. Unlike virulent strains of Marek's disease virus, which are highly contagious, turkey herpesvirus is not readily transmissible among chickens (although it is easily transmitted among turkeys, its natural host). Attenuated Marek's disease virus strains vary greatly in their transmissibility among chickens; the most highly attenuated are not transmitted. Marek's disease virus is not vertically transmitted. Vaccination is the central strategy for the prevention and control of Marek's disease. The efficacy of vaccines can be improved, however, by strict sanitation to reduce or delay exposure and by breeding for genetic resistance Vaccines are also effective when administered to embryos at the 18th day of incubation. In ovo vaccination is now performed by automated technology and is widely used for vaccination of commercial broiler chickens, mainly because of reduced labor costs and greater precision of vaccine administration. under typical conditions, vaccine efficacy is usually >90%.
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