For those that use this product be aware that it will NOT protect your animals from tick borne illnesses. I have 4 dogs, all over 60 pounds. I have religiously treated them with Frontline Plus to, I thought, protect them from the millions of ticks. Wrong, so very wrong. Two of my dogs have been confirmed to have ehrlichiosis, a third one needs to be tested. At this point I'm considering just having my vet put the last two on the Doxy because the last place they want to be is in my truck going to the vet. I've spent close to two hundred dollars the past two weeks on drugs, vet visits and testing. That does not include the one hundred dollars it costs to pick up the package of Frontline Plus that is supposed to be protecting them from these diseases. There are other products out there that are available but be very careful and check with your vet before purchase, some of them are very toxic to cats and may be toxic for other species as well. The species of tick that gives this disease to our dogs is the dog tick and the deer tick. Two of the most common ticks.