I am trying Valtrex (an antiviral drug for human herpes) on two pullets that are showing signs. Has anyone else had success with this? I understand it works by blocking an enzyme that the herpes virus uses to replicate. I am pretty sure I have Marek's in my small flock. Never officially diagnosed but I have lost a few "stressed" birds in the last year and all showed the same signs. Did have a necropsy done on the first bird but because they did not see lesions they said it was not Marek's, now I know that lesions are often not found. I did find a youtube video (below) of a man that tried it twice and got good results. Of course the disease could have naturally gone into remission and maybe it is just a coincidence, but it is worth trying as otherwise I expect my two pullets will die. Here is the youtube video I referred to.