Please bear with me, this is long, since this story is still developing even since this morning. I filled out the questioner at the bottom of this post regarding symptoms and environment and such. We are very concerned that we may have "late" mareks or something of that nature. I was out playing with, and spending time with our small flock of 5 and noticed my light Brahma hens eyes on 4-19-2012. I was taken back, and thought it was odd. The next day I did a little looking online and this looks suspicious of "late" mareks. These are pictures of her eyes. This is Castelli a 1 year+1month old Light Brahma hen who has been eating/drinking/and laying normally so far.(I assume that will all change soon) Sorry, everyone is a little soggy since it was a rainy morning here. Even more detrimental, was when I went to photo my LB this morning, my SLW Spaghetti, was standing with her eyes closed and is not very responsive to her environment…. Which is a 180 turn from yesterday The below two are close ups of here eyes and face. I assume my flock is all fully exposed to whatever it is. It is more apparent now that I may not have connected the dots/symptoms sooner in my GLW Spencer who seems to be on death row. I don’t know her actual age since she was adopted three years ago. When I got her she was already mature and laying, so I’m guessing she is between 4-5 years old. She first began having issues around 3-19-2012 This link/thread is the beginning of my GLW troubles and I'm assuming she may have exposed all of them? https://www.backyardchickens.com/t/640704/egg-without-shell-whats-with-this-egg At the time I did not know who was laying eggs with extremely thin shells, but know I am confident it my GLW. She has lost a lot of weight suddenly and is very skinny. Most suggestions/reasons on the forum for a chicken losing weight was to worm them. At the time it did not seem a big problem, and I did take her from the flock. (We have a micro flock of 5 and it causes extra stress to remove and add birds.) As soon as I realized she was losing weight, she got wormed with safeguard. She just finished her second treatment 4-19 and is in worse shape them ever. She has gone from our hardest working fattest chicken to a thin and lethargic girl. We have been feeding her extra food like cottage cheese, yogurt, canned salmon, and egg to help her get some weight on. This week she has been losing interest in food. I don’t think she will be with us much longer…. This week I have begun to consider culling her since it seems her comfort level is going down ***I have no idea if any of the birds I own were ever vaccinated for mareks. MY GLW was adopted as a mature bird 3 years ago. My BO bought as a pullet from a farm 2 years ago, and three were bought as chicks last spring from Farm and Home 2SW, 1 LB. The GLW is 4-5 years old, the BO 2 years old, and the SLW &LB are 1 + years old. I assume this is the end for my very very loved flock If so, what will I need to do to prevent this from happening when they are replaced? What do I do and how long? If not, what do I do? Cull the birds showing symptoms? IF I add more birds later does that mean my birds that may have immunity will infect my new birds? 1) What type of bird , age and weight (does the chicken seem or feel lighter or thinner than the others.) 3 wyandottes-2 1 year olds-1, 4+ year old 1 buff orpington-2 year old, 1 light Brahma-1 year old 2) What is the behavior, exactly. GLW-has become quickly emaciated, losing interest in food, slowing down.. LB-Notice change in eyes SLW-closing eyes, not responsive/alert to endowment 3) How long has the bird been exhibiting symptoms? The GLW began with thin eggshells around 3-19-2012 The LB I noticed 4-19-2012 SLW noticed 4-22-2012 4) Are other birds exhibiting the same symptoms? Not that I can see 5) Is there any bleeding, injury, broken bones or other sign of trauma. NO 6) What happened, if anything that you know of, that may have caused the situation. Unsure 7) What has the bird been eating and drinking, if at all. 4 birds are eating, drinking normally. They are fed Layina laying crumbles with free choice grit and oyster shell. They are also allowed to free range some in the yard, and get occasional treats. -GLW have been feeding extra yogurt, cottage cheese, canned salmon, cooked egg, now losing interest in food altogether. 8) How does the poop look? Normal? Bloody? Runny? etc. 4 normal to the best of my knowledge…. GLW- abnormal-mainly liquid, very little poo that can be green 9) What has been the treatment you have administered so far? GLW-feeding extra protein wormed with safgaurd. They were all wormed last over the winter. 10 ) What is your intent as far as treatment? For example, do you want to treat completely yourself, or do you need help in stabilizing the bird til you can get to a vet? I need advice, I am scared that this is the end of my precious flock. 11) If you have a picture of the wound or condition, please post it. It may help. Posted eye pics 12) Describe the housing/bedding in use chicken tractor, bedding is compressed wood pellets and wood shavings... We are religious in scooping the poop out of the tractor each day. This is easily done with cat scooper's and the compressed wood pellets. The tractor is moved around the yard frequently to keep the grass from being completely destroyed. We have screen on the tractor during the summer to keep out pests like gnats. That is why it appears dark in the photo. Thank you for reading, I know this is long!!!