I posted this originally in an older thread, but there's been no activity so I'm starting a new thread so I might be able to get some information. As of today, they still sound awful, the one who was sounding the worst, seems a bit lethargic today. They sounded a little better yesterday afternoon, but after I did the second misting with the oxine, they seemed to go downhill by this morning. This is the content from the original post. It was #69 on page 7 of this thread from 2012: https://www.backyardchickens.com/t/...staken-for-crd-mycoplasmosis/60#post_17212538 "....Over last week, we had unseasonably hot weather culminating on Saturday which was said to have been the hottest day on record in a while. It's June, but feels more like august. Like most folks, I had a misting hose set up to cool the yard a bit, and typically have a box fan set in a small portion of the run so there is decent air flow. Oftentimes, this is where the ladies will congregate to keep cool. Saturday was so bad that I actually turned the fan on the highest setting(something I never did before). Yesterday morning, one of my birds sounded like a percolator. I immediately separated her and began treating with Tylan 50 injectable, given orally at a dose of .50ml. It was right before we were set to leave for a day trip kayaking on the river. When we got back that evening, I went to check on the rest of the flock to see if any others showed symptoms. 2 did, so I pulled them also, and started the Tylan. Today, I decided to use Oxine as a mist in my fogmaster jr, as I have all 3 corralled in my bathroom. I am planning to continue the tylan for the specified time frame(as I have no proof that it is fungal vs bacterial) and also to mist twice a day with the oxine in the event that it is. My suspicions, after reading speckledhen's many posts about fungal infections, have me leaning towards this after considering the fact that the only birds affected by this percolating sound are the 3 who spent all of their time in front of the fan. The first bird separated, sat about 2 inches from the fan on high, for all of Saturday. I went out this morning to observe the rest of the flock and no other birds sound like this. They were the ones who were roaming the yard more freely and spent most of their time in a shady area across the yard. Does this course of action sound reasonable to anyone? Anything you might do different or suggest something else I may not have considered? " edited to add: they seem to still be eating and drinking, at least a little bit. I appreciate anyone who takes the time to read this and respond. Thanks! UPDATE: Many hours later I am now dealing with the worst of the bunch sounding like she's drowning and she's got one eye closed. IS ANYONE interested in giving a girl some advice on how to proceed?