I recently had a problem with Mites and Lice in my flock brought in by some new birds. Someone mentioned using the Frontline Spray so I was doing some research on it before I use it. I found the following article on a breeders website about how to use Frontline on chickens. Mites and Lice in Poultry At some point in time, everyone who raises poultry will find they have some kind of unwanted pest living on their fowl. This is especially true of the crested breeds. Because these birds have very feathered heads it makes them a target for mites and lice. We try to check our birds weekly because the sooner you catch them, the easier they are to get rid of. To check your bird, pick it up and look at the feathers. Spread the feathers apart and look at the bases of the shafts and also the skin. Look for tiny insects crawling along the skin and on the feather. These may be black, reddish, or cream colored. Also pay attention to the down at the base of the feather shaft. Look for egg sacs, that are white or cream colored, attached in clusters to the shaft of the feather. When we find any of these signs, it's time to treat the birds. There are several different products available to treat mites and lice, however, we use just one product here. Frontline Spray is what we have found to work wonders. When explaining this product to people, they often times confuse it with the little tubes of spot on that is used as a once a month flea treatment for dogs or cats. While made by the same company, it has a different dosage of the active ingredient and should not be used. What you want is the spray bottle that has the trigger sprayer top on it. It comes in various sizes, with 250ml probably being the most common. While it is a little expensive, to us, it is well worth the cost. This product has not been tested and approved by the company for use on poultry used for table eggs or meat. Therefore, the use of Frontline Spray described below is only for informational purposes when dealing with show birds whose eggs or meat is not consumed by people. There are two methods of applying the spray to the bird. One that is used by some breeders I have talked to is to spray the bird with a mist from the bottle. They will adjust the nozzle and spray them with a pump or two of the trigger, just enough to wet the surface of the feather. I have found another method that works better for us in all but the extreme infestation cases that occasionally pop up because you missed somebody during a mite check. What we do it to take an eye dropper bottle like a contact re-wetting drop bottle and use this. The dropper part of the bottle will pull out from the body, then just squeeze the trigger on the Frontline a couple times, directing the stream into the dropper bottle to fill it. I will take this dropper bottle and place one drop in the crest, one under each wing, and one on near the vent either on the abdomen or tail bone. Spread the feathers apart and get the drop of liquid right onto the skin. If you find this too dificult, then you can use a cotton swab saturated with the liquid and apply it right to the skin in the same spots. While we have not had any cases of scaly leg mites, we have been told that misting the legs or rubbing them with a soaked cotton ball of frontiline will quickly end leg mite issues also.