A vet drug book I have says that one level teaspoon of Tylan powder has 2500-2700 mg tylosin, so I think I'd pick the lower number just to be sure they get enough medication.
Try taking 1 level teaspoon (2500 mg), add 25 ml of water and see if it dissolves. If it dissolves, give your 4 pound...
With your rooster, I know what you mean about the mass being everywhere, and yes, those are harder to treat due to the way it invades the entire sinus cavity. The feed store I go to had a peahen like that and it took me several days to get all of it out, but she did live.
With your poult, you...
Disclaimer: I have no medical training.
I think you poult needs sinus surgery no get all the pus out. As long as any pus remains it will keep filling up. Read this:
http://connerhills.com/sinus_infection_removal.html
If she's not drinking ant eating you will need to tube feed her. How much...