Anyone Here Good at Math? - Math and Medications

[casportpony]

This is meant to be a fun exercise

Exercise Number One


First up is 9.6% amprolium.

Brand name Corid is labeled cattle, so let's use the instructions for AmproMed instead. They are the same, both are 9.6% ampolium.


Source: http://www.animalhealthinternationa...Training/Bimeda/AmproMed-P-Poultry-Liquid.pdf

Given the above, how do you make a a gallon at the three different levels?

-Kathy

 

[Free Spirit]

Ugh Math ! LOL
Starting with your first post: in US measurements

If the directions say for a mix at 0.012% = "8 fl oz per 50 gal" then we need to find how many ounces per gallon.
50 gallons divided by 8 ounces = 0.16 oz solution per gallon

1 Teaspoon = 0.166666667 (1/6) Ounce
1 Teaspoon = 4.92892159 Milliliters

The first is a normal dose. The second is 2x dose for severe. The third is 1/2 of normal dose. So the answer is as follows:

0.012%: .16oz solution per gallon = 0.96 tsp = 1 tsp or 4.73 ml - for normal solution.
0.024%: .32oz solution per gallon = 1.92 tsp = 2 tsp or 9.46ml - for stronger solution.
0.006%: .08oz solution per gallon = 0.48 tsp = 1/2 tsp or 2.36 ml - for the remainder of treatment.

Now to work on the second part of your query.

 

[Free Spirit]

Exercise Number Two


What the above picture says is that the dose should be 20 mg of amprolium per 1kg (kilogram) of bird weight.

Calculate doses for the following:

• 2 ounce chick
• 7 ounce chick
• 1 pound bird
• 10 pound bird

Show your work!

-Kathy

More conversions needed to get from ounces and pounds to mg/g/kg:

1 kilogram (kg) = 1000 grams (g) = 1000000 milligrams (mg) ( multiply kilograms by 1,000 to get grams or multiply 1,000,000 to get milligrams)
1 ounce (oz) = 28349.52 mg or 28.34952 g or 0.02835 kg (divide 28349.52 milligrams by 1,000 to get grams or divide by 1,000,000 to get kilograms)
1 pound (lb) = 16 oz

Lets first calculate bird weight in kilograms using the formulas above:

2 ounce chick = 0.02835 kg x 2 oz = 0.056 kg
7 ounce chick = 0.02835 kg x 200 oz = 0.19845 kg
1 pound bird (1 lb is 16 oz) = 0.02835 kg x 16 oz = 0.4536 kg
10 pound bird (10 lb x 16 oz = 160 oz) = 0.02835 kg x 160 oz = 4.536 kg

Now for the amprolium at 20 mg per kilogram of bird. Easy... now you just multiply 20 times the bird weight in kilograms:

2 ounce chick = 20mg x 0.056 kg = 1.12 mg of amprolium
7 ounce chick = 20mg x 0.19845 kg = 3.969 mg of amprolium
1 pound bird = 20mg x .4536 kg = 9.072 mg of amprolium
10 pound bird = 20mg x 4.536 kg = 90.72 mg of amprolium

 

[Free Spirit]

Exercise Number Four


What are the per liter doses for the following:

• 0.024%
• 0.012%
• 0.006%

-Kathy

It seemed too easy I had to check it several different ways and still came up with the same answer. Here's one method:

1 gallon = 3.785 L (listed on the package of amprolium)
50 gallons = 189.27 L
1 Liter = .26 gal
1 ounce = 29.5735 ml

16 oz = 473.176 ml
8 oz = 236.588 ml
4 oz = 118.294 ml

0.024%: 473.176ml divided by 189.27 L = 2.5ml/L
0.012%: 236.588ml divided by 189.27 L = 1.250ml/L (or 2.5 divided by 2)
0.006%: 118.294ml divided by 189.27 L = .625ml/L (or 2.5 divided by 4)

These are in US measurements. UK measurements will be slightly different.

 

[Free Spirit]

Yeah these instructions are totally bizarre.

Let's start with some basic formulas (based on the internet conversion chart supplied with the package instructions in the original post). We'll use these for the examples given.

0.25oz = 7.087g
0.50oz = 14.174g
1oz = 28.349g
2oz = 56.699g

Let's just bypass the Tablespoons for the moment and use only measurements in grams (mass weight).
Calculating both 400mg and 800mg solutions to figure out how many gallons a package will make.

Starting with the bad (package instructions):
400mg: 181g divided by 28.349g (1oz) = 6.38 gallons of solution per package
800mg: 181g divided by 56.699g (2oz) = 3.19 gallons of solution per package

What the package should read:
400mg dose = 1/2 Tbls (.25oz) per gallon of water
800mg dose = 1 Tbls (.5 oz) per gallon of water

Then the math works after you convert ounces to grams
400mg: 181g divided by 7.08g (1/4oz) = 25.53 gallons of solution per package
800mg: 181g divided by 14.174g (1/2oz) = 12.76 gallons of solution per package

I haven't worked that out in Tablespoons yet. Volume and Mass don't always mix and since the package instructions are wrong

.

Of course you don't have to convert anything to grams ounces work to:
800mg: 6.4oz divided by .5oz = 12.8 gallons

 

[Free Spirit]

Here is the 0.012% mixing instructions for the Corid Powder.


Confirmed with the mfg that the 0.024% dose is 4.536 grams.

-Kathy

Corid 20% Soluble Powder
Package weighs 10oz (283.5g) = 35 Tbls = 200mg Amprolium per gram

Formulas for conversions:
1oz = 29.5735ml
1oz = 28.3495g
1oz = 3.5 (3-1/2) Tablespoons (by weight for Corid powder only)
1oz = 10.5 (10-1/2) teaspoons (by weight for Corid powder only)

How much powder to mix to make one gallon of solution for each strength.

0.024% solution for severe outbreaks: give for 5 days
8oz/50gal = 8oz divide by 50 = 0.16oz/gal
8oz/50gal = 236.588ml divide by 50 = 4.73ml/gal
8oz/50gal = 226.796g divided by 50 = 4.536g/gal
8oz/50gal = 28 Tbls divide by 50 = 0.56 Tbls/gal (approx. 1/2 Tablespoon)
8oz/50gal = 84 tsp divide by 50 = 1.68 tsp/gal (round up/down to 1-1/2 to 1-3/4 teaspoons per gallon)

0.012% normal solution: give for 5 days
4oz/50gal = 4oz divide by 50 = 0.08oz/gal
4oz/50gal = 118.294ml divide by 50 = 2.37ml/gal
4oz/50gal = 113.398g divide by 50 = 2.27g/gal
4oz/50gal = 14 Tbls divide by 50 = 0.28 Tbls/gal (approx. 1/4 to 1/3 Tablespoon)
4oz/50gal = 42 tsp divide by 50 = 0.84 tsp/gal (round up/down 3/4 to 1 teaspoon per gallon)

0.006% 21-day preventative solution: give for 21 days
2oz/50gal = 2oz divide by 50 = 0.04oz/gal
2oz/50gal = 59.147ml divide by 50 = 1.18ml/gal
2oz/50gal = 56.699g divide by 50 = 1.133g/gal
2oz/50gal = 7 Tbls divide by 50 = 0.14 Tbls/gal (approx. 1/8 tablespoon)
2oz/50gal = 21 tsp divide by 50 = 0.42 tsp/gal (round up/down 1/3 to 1/2 teaspoon per gallon)


Clear as mud?

 

[casportpony]

Exercise Number Two

Second up is how to calculate an oral drench of 9.6% amprolium based on this:

Source: http://www.manorvets.co.uk/ckfinder/userfiles/files/Manor chickens.pdf

What the above picture says is that the dose should be 20 mg of amprolium per 1kg (kilogram) of bird weight.

Calculate doses for the following:

• 2 ounce chick
• 7 ounce chick
• 1 pound bird
• 10 pound bird

Show your work!

-Kathy

Edited to change 200 ounce to 7 ounce

 

[casportpony]

I think it's interesting to see how different people come up with the answers! Thanks for sharing.

-Kathy

 

[Free Spirit]

I think it's interesting to see how different people come up with the answers! Thanks for sharing.

-Kathy

It would be great if UK members can work it out too because the measurements are slightly different in metric. I only used the US system of measurement.

 

[casportpony]

Exercise Number Three


How many milligrams (mg) of amprolium are there in:

• One gallon at the 0.024% level = ??? mg
• One gallon at the 0.012% level = ??? mg
• One gallon at the 0.006% level = ??? mg

-Kathy