I would not recommend trying to mix Tylan 50 or Tylan 200 in drinking water. What's important is that each sick bird get 55mg/kg twice a day for at least three days. Tylan (tylosin) will treat some bacteria, but not many, and @IceAngel is correct, it will not treat coccidiosis.
This table lists some of the bacteria it treats:
![](https://www.backyardchickens.com/content/type/61/id/6998396/width/500/height/1000)
-Kathy
This table lists some of the bacteria it treats:
-Kathy