I've been using the DE for the chickens, horses, goat and dog. They all get it in their feed and of course the other uses members have already stated. Also, you can use it in your garden if you have one. I also put it in my flower beds because the girls like digging up the dirty and rolling around in them. This way they get it on their skin to help with the mites.
They only place I could find it locally was at my feed store, non-food grade for $9.00 for 4lbs. I went online and found food grade 50 lbs with shipping it was $50, Earthworks. I know it sounds like a lot, but it goes such a long way with so little and just about everything on your property can injest it.
I worm my dog every month, but by about week three I started noticing he's starting dragging his rear end across the floor, dirt, whatever. Since he's been getting the DE everyday mixed in with his dry food and a tablespoon of water to help coat the food, he doesn't do that any more. It seems to help.
I also have a horse who has heaves. He's been on an herbal supplement for three years that contains DE. He had to go to the horspital this past spring. They tested him for worms, which is normal, and they asked what my worming routine was because he only had two eggs in his stool sample which is unheard of, it's usually around 20-30 for a well wormed/maintained horse. I explained my routine and mentioned the DE in the supplement. They were impressed and told me to keep up the good work, perhaps all horses should be on a little DE. So now they all get it daily.