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Here is some reading: about air sacculitis: http://www.poultrydvm.com/condition/airsacculitis https://www.mypetchicken.com/backyard-chickens/chicken-help/All-about-Airsacculitis-disease-H387.aspx Some articles on MG...

Where are you located? Get a necropsy by the state vet if you lose another. That will diagnose the respiratory disease and if there is a secondary infection. Since you saw some improvement with Tylan, it may be MG, but E.coli can cause air sacculitis during an MG or other bacterial respiratory...