I live by a creek which serves as a wildlife highway. I've personally seen owls, hawks, eagles, weasels, raccoons, possums, coyotes, stray dogs, bobcats, and a juvenile black bear. I rely on the fact that I'm usually at home, and the coop/run are close to the front of the house, and I have 3...
The run might be "predator resistant" for your area (mine is similar, just taller) but it's definitely not predator proof enough that I'd feel safe letting them sleep in the run.