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I haven't lost any of the cresteds we have had, so I wouldn't be excessively worried about it. ours seem as robust as the rest of the ducks. knowing that they may have cranial bone abnormalities, just be aware when you're handling them and you should be fine.
I seem to recall that the crested gene is a dominant one, meaning that if a duck has one copy, it'll have a poof, if it has 2 copies, the skull won't close and it generally fails to hatch late in development. what I think that means is if you breed 2 cresteds, on average, in four eggs you get 1...