I am actually using Chrome, not FF and I do have the columns turned to full width. I have no issues with speed or anything like that, it's just the color effect on my browser/monitor is very jarring.
Edited to add: Trying to narrow the problem down, I don't think it is the color of the blue...
2nd this, I don't think it's just your monitor. I am having the same problem where it hurts just to look at the page.
I completely understand the need for a new platform, but perhaps the colors could be toned down to make them more eye friendly.