With the structure off the ground the only thing that should be pressure treated is the posts. I would put the posts below frost line in your area otherwise your building with rack up and down each spring. Most soils wont hold that large a structure on little cement post stands- they will...
If you use piers in the middle then you'd be making a beam those piers would support and have two spans for joists. If that's your want then go ahead but it's easy to get 12' lumber so why not just have a 12ft span. Use 2x8's graded structural or No 1 and spacing of 2ft. I'd use joist hangers...
If you did use 2x6 for floor joist then 2ft on center is sufficient. You've got to keep in mind a residential building is designed for 50 lbs per square foot of load. A 2x4 16 inches on center provides that for 8 ft span. That means it can hold 8x12x50 lbs (that's over two tons) without...
You can get away with only post for 4 corners, for more support you can add a post at 6 ft on 12 ft side which is a good idea as the actual floor joist will be attached to that frame. Double up the outside joist, screw 2 together. Also you only need 2x4's for the actual floor joist. Run them the...