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So sorry for your loss, and it's good that you kept her from suffering.

It could be be a tumor, but it could have been injured or from a predator. I would suggest soaking the leg once a day in warm epsom salts or betadine and water. Dry the leg and apply an antibiotic ointment or Vetericyn, and wrap it in gauze and vet wrap to keep her from biting it. The black...