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Yes it needs to come out or it will keep getting worse. Neosporin ointment helps the scabs to keep from sealing.

Pictures of the comb and wound would be very helpful. Are there scabs on the comb or it is just darkened? I would clean the wound once with hydrogen peroxide letting it bubble for a few minutes, or if you don't have it then put a warm soap wet wash cloth on it and hold her for about 10 minutes...