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That niacin should be fine. You'll want to crush it really fine, and add 100-150 mg per gallon of water and stir it until it dissolves. One of those pills would be good for about a gallon and a half to two gallons of water.

It looks like a birth defect, and I don't think there's anything you can do about it. Is he eating and drinking ok? What kind of niacin are you giving? It needs to be plain niacin. Not flush-free, not timed release. You can use brewers yeast or nutritional yeast on their food instead, too. One...