I only had 3 chicks (brooded in a bathtub) and by 5 weeks I could smell them from down the hall. Plus the dander they left reached all the way up the shower wall, to the overhead window, across to the sink... it's like cleaning a greasy kitchen, words can't describe it!
Having them in separate brooders is fine, they don't really form a strict social order until they're older so there's no need to worry that they can't integrate easily while young.
You're probably going to regret having them in your office though. The smell from 16 chicks will be... something...