I've seen these types of statements several times on BYC. They are not factual. Amprolium is a vitamin B1 (thiamine) analog. It competitively blocks thiamine usage by the parasite. The host (chicken) is much less sensitive to thiamine deficiency than the parasite. That's why is it effective. Sulfa drugs interfere with folic acid synthesis. They prevent the parasites from making the folic acid they need to survive. The chicken, however, can get all the folic acid it needs from its diet. This difference is what makes sulfa drugs effective. Amprolium is not a sulfa drug, therefore, there is absolutely no risk of sulfa allergy from Amprolium.
This is the structure of Amprolium. It has so sulfur in it.
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This is the structure of Amprolium. It has so sulfur in it.
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