Humans can contract E.coli from handing chickens however not all that common. Just the same, always wash your hands after handling your birds.
As for the eggs, its always a good idea to thoroughly cook your eggs and meat. No half cooked eggs or rare meat. Cook food completely through and you should be safe from E.coli.
Cleanliness in and around the coop and run is the key to good health in your birds. All warm blooded creatures, chickens and humans alike, have a certain amount of E.coli present in the intestinal tract. However when birds become overwhelmed with it in their environment, it can make them sick from an over growth of it in their guts. Keep the grounds as clean as possible and this shouldn't be an issue.
