℞ Calculating Medication Doses - under construction ℞

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Due to some confusion earlier, I thought I should start this thread. The drug I am going to use as an example is enrofloxacin and that's because it comes in so many strengths. Yeah, I know it's banned for use in poultry, so let's keep the "no to enrofloxacin posts to a minimum" :) Those that don't know about the ban should read this:
https://www.fda.gov/AnimalVeterinary/SafetyHealth/RecallsWithdrawals/ucm042004.htm

Step One - Figure out what strength the product you have is. Something like enrofloxacin (Baytril) comes in many forms.
  • 10% (100 mg/ml)
  • 5% (50 mg/ml)
  • 2.5% (25 mg/ml)
  • 2.27% (22.7 mg/ml)
  • Custom made by a compounding pharmacy
Step two
  • Is it an oral or an injectable?
These are injectables and can be given by injection or orally:
baytril_10_inject_1.jpg baytril_5_0_inject_1.jpg baytril_2.5_inject_1.jpg baytril_2.27_1.jpg baytril_2.26_1_generic.jpg baytril_enfloxil_5_1.jpg baytril_enfloxil_2.jpg baytril_enfloxil_1.jpg enroxil_10_inject_1.png enroxil-5-50-ml.jpg

These are oral and should be given orally, never by injection.
zoopan_enroxina.jpg baytril_10_oral_1.png baytril_2.5_oral_1.jpg baytril_enroxil-10-1-litro_grande-500x500.jpg

Step three - What dose and how to give it.
  • The most common dose seems to be 10 mg/kg *orally* twice a day.
  • One person on BYC reported that their vet prescribed 15 mg/kg twice a day for their goose.
  • Some books say it can be given once a day.
  • Some books say oral (PO), some say injection in the muscle (IM), and some say under the skin (SC or SQ).
Plumb's:
baytril_1.jpg baytril_2.jpg

Clinical Avian Medicine
enrofloxacin_2.JPG

Avian Medicine: Principles and Applications
enrofloxacin_1.JPG



Step Four - Weigh your bird. For semi-quiet birds under 5 kg (11 pounds), I use a kitchen scale. For the bigger more squirrely types I use a bathroom scale. To do that weigh yourself first, then weigh yourself hold the bird. The difference between the two numbers is the weight of the bird.

When I weigh birds I prefer to use the metric system, but if you choose to weigh in pounds just be ready for a little more math.


Step Five - the math
If you weighed in pounds:
The weight of bird in pounds, divide by 2.2 to convert to kilograms, times desired dose (mg/kg), divide by number of milligrams in one ml (mg/ml)

If you weighed in kg:
The weight of bird in kg, times desired dose (mg/kg), divide by number of milligrams in one ml (mg/ml)

If you weighed in grams:
The weight of bird in grams, times 0.001 convert to kilograms, times desired dose (mg/kg), divide by number of milligrams in one ml (mg/ml)

Step six - Give the medication.​
  • IM - Give in breast muscle. im_injection.jpg

  • SC or SQ - Give under skin. subcutaneous_injection_1.jpg Subcutaneous-fluid-diagram.jpg





ug = microgram
mg = milligram
g = gram
kg = kilogram
l = liter
ml = milliliter

PO - orally
IM - Intramuscular injection (injection into muscle)
SC or SQ - Subcutaneous injection (injection under skin)

SID - once a day
BID - twice a day
TID - three times a day


mg/ml = milligrams per milliliter
g/l = grams per liter
mg/kg = mg per kilogram

Convert pounds to kilograms - Pounds ÷ 2.2 = kilogram
Convert kilograms to pounds - Kilograms x 2.2 - pounds
 
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POUNDS
800 grams = 1.76 pounds
Med #1 1.76 divided by 2.2 times desired dose 20 divided by 100 = .16ml
Med #2 1.76 divided by 2.2 times desired dose .2 divided by 1.5 = .10ml

(poundage divided by 2.2 times the dose (mg/kg) divided by the total strength(mg/ml))



GRAMS
800 times .001 times 20 divided by 100 = 0.16ml
800 times .001 times .2 divided by 1.5 = 0.10ml

(grams times .001 times dose (mg/kg) divided by strength (mg/ml))
 
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