Oxine antifungal information

[Goosebaby]

I don’t like just taking someone’s word for something, it’s caused problems for me in the past and let’s be honest, a lot of people spread bs around without realizing it’s bs, like the medicated feed toxic to waterfowl myth for example.

So I was curious about Oxine’s supposedly curing birds of aspergillosis and I really wanted to know more.

I’ve seen a lot of people say it has cured their birds, if so that’s wonderful!
But I haven’t found any confirmed case studies or research on it.

Looking around online I’ve found that Oxine or if you go by it’s other names “8-hydroxyquinoline; oxyquinoline; 8-quinolinol” does appear to have antifungal properties against species of Candida and Aspergillus Niger among others.

Articles I’ve found:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323154/

https://pubmed.ncbi.nlm.nih.gov/32941027/

http://tchie.uni.opole.pl/ecoproc08b/Nabrdalik_Disinfective_08b.pdf

https://www.jstage.jst.go.jp/article/biochemistry1922/72/4/72_4_833/_article


What I haven’t found is any information of how Oxine specifically affects Aspergillus Fumigatus, which is the most common cause of aspergillosis in birds and humans. I suppose it has some effect, as it seems to effect a lot of other mold species, but without any published studies there’s no way to say how sensitive A. Fumigatus is to it and if Oxine is an effective treatment, or what dosing to use or how long.

If anyone has any information on this please let me know in the comments!

 

[Isaac 0]

You are going to find a hard time finding studies relating to the use of oxine as an agent in treating respiratory issues in a controlled setting simply because that is not one of the product's intended applications.
Oxine is used by many poultry owners as the last resort where a veterinarian can not be seen. As far as I'm concerned, all accounts relating to its use in poultry as nebulization therapy are anecdotal. If you are looking for a safer, studied alternative in antifungal treatment, you should consider speaking with your veterinarian. Agents such as Amphoteracin may provide a better outcome.

 

[Goosebaby]

You are going to find a hard time finding studies relating to the use of oxine as an agent in treating respiratory issues in a controlled setting simply because that is not one of the product's intended applications.
Oxine is used by many poultry owners as the last resort where a veterinarian can not be seen. As far as I'm concerned, all accounts relating to its use in poultry as nebulization therapy are anecdotal. If you are looking for a safer, studied alternative in antifungal treatment, you should consider speaking with your veterinarian. Agents such as Amphoteracin may provide a better outcome.

Thank you!