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I did when it was smaller and it was not successful. Now it is advised to not cut into it.

Yup

My girl has the infection on both feet and it is running up her leg. That is why I refrained from buying the 110g. Idk if it will help her this late on.

Thanks to this thread I finally got my butt moving and ordered the tricide neo for my girl. I almost ordered the 110g instead of the 22g for over double the price, but I want to see if it will actually work before I buy the larger, more expensive quantity.