Yes, don't do it. Her size won't matter, they'll still gang up on her and it won't be pretty and can do her serious harm or even cause her death. I had 2 male Rouens and 2 large female Pekins and the Rouens thought nothing of together ganging up on each of the Pekins even though the females were significantly larger than the males and it was really, really brutal. I finally had to separate the males from the females during this breeding season and the males called to them constantly terribly through the fence. Don't do it to the female -- it wouldn't be fair to her. There's a reason for having 3 or more females per drake and that's for the female's health and safety!