Mareks in the flock does change things. It causes low white blood cells, and poor immunity to the common diseases. Where most chickens can shake off something with a good immune system, chickens who are Mareks positive may get more illnesses. When antibiotics are used before testing, it can affect getting a positive test. So good that you have a vet visit coming up. Let us know what happens, and I hope that your birds stay healthy. Many people on BYC deal with Mareks in their flocks. While they have losses, many continue to have good luck with the survivors. I would vaccinate any new chicks, and only breed birds who do not show symptoms. After vaccinating, if you choose to do that, chicks need to be kept from any exposure to feather dander and dust for at least 2 weeks. Repeated vaccine has been shown to provide more immunity. There is plenty of info about that online if you search.