Healing time can vary depending on the size of the lesion. I don't isolate unless the bird is having trouble getting around. If it's wrapped well it should stay clean between changes. Unless you have really wet or damp or dirty conditions. I usually change dressings daily and reapply whatever ointment you are using, until I know it's healing well, then you can go to every other or every third day as needed. If it's wet where she is then more frequent changes might be necessary.