If you have access to a tractor, then sure, knock yourself out -- I would still recommend making the house and run portions as 2 separate units that lock together once they get where they're going, though.
If you try to use a tractor to move the chickens locked into the house portion, that is going to be an extremely bumpy and upsetting ride for them. Unless the chickens are free-ranging, you will probably have to lock them in the house, move the run and block off its open side, then move the chickens manually (cardboard boxes or pet carrier), then move the house portion and reattach it.
If there is very high predator pressure, you COULD do a wire bottom to the run (use good welded wire, not chickenwire, though), but the chickens won't like it nearly so much because they so like to scratch. A better option is normally to either put the chicken tractor inside a fenced area so there is some extra level of defense vs predators, and/or to have a welded wire mesh 'skirt' that lies on the ground all around its edges (firmly attached to the tractor, e.g. by hinges so you can flip it up for moving) for a width of AT LEAST 6" and preferably a good bit more. That way the chickens can still scratch and dust unimpeded.
Good luck, have fun,
Pat