I'm not particularly sensitive to poison ivy/oak. I will find a few small blisters when I get into it, but not bad. But I'm still careful around it cause you can develop sensitivity to it. I don rubber gloves and pull up (root and all) what I can. If I can't get the root up, I spray it with brush killer, but just the root. That usually does it. When I'm done, I go in and wash my hands and arms with Tecnu. You can get it at most any drug store. It works well I know cause my grandkids are all extremely sensitive to poison ivy/oak and it keeps them from breaking out too.