pips&peeps :
....Yes, clean the coop and most common area they spend time in with oxine, it will kill the oocytes.
Oxine will not kill the oocytes
http://attra.ncat.org/attra-pub/coccidiosis.html
from an excellent article from ATTRA:
"...Knowing how coccidia develop helps to understand and control the disease. Coccidiosis is caused in poultry by a one-celled parasite of the genus Eimeria. The life cycle of Eimeria takes about four to seven days to complete. It begins when active oocysts are picked up by the bird and swallowed. An oocyst is a capsule with a thick wall protecting the parasites. They sporulate or become infective if moisture, temperature, and oxygen become conducive to growth. After a bird eats the oocysts, coccidia imbed in the intestinal lining and multiply several times, damaging tissue.
Coccidia are parasites, so they get their nutrients from the chicken host. The multiplications eventually stop, usually before causing death of the bird. The bird sheds the parasite in its droppings. These new oocysts can infect other birds....Coccidiosis goes hand-in-hand with gut diseases, because it damages the gut and allows bacteria to enter and cause secondary infections.....Management has always been important to coccidiosis control, especially before drugs were available. Management focuses on reducing the number of coccidia to keep infection at a minimum until immunity is established....A small-scale, low-density production system can allow a low level of exposure to coccidia, which permits the chick to develop immunity without triggering the disease. However, birds may not pick up enough parasites to cause immunity, or they may be overwhelmed by too many. In addition, immunity is only species-specific. Exposure to one type of coccidia will not protect a chicken from the other six types that can infect it. ....
Sanitation
Disinfectants are not effective against coccidia, so sanitation focuses on good hygiene and removing infected droppings.
Put waterers and feeders at a height level with the backs of the birds, so they cannot defecate or scratch litter into them. Keep birds from roosting on the feeders with anti-roosting wire. Suspend waterers or put them on wire-covered platforms to help keep them clean.
Clean the waterers and feeders frequently.
Keep older birds away from chicks, since old birds are carriers....
Natural Treatments
Keeping birds in general good health is always important. Some small producers provide raw milk, yogurt, apple cider vinegar, or probiotics to birds, believing that beneficial microbes will prevent or treat coccidiosis.
Actually, coccidia do not compete with bacteria in the gut; therefore, beneficial bacteria and other microbes will not eliminate coccidial development. However, anything that improves the overall health of the gut and the bird can help reduce the
impact of coccidiosis. Also, a population of beneficial bacteria is always better than pathogenic bacteria, since coccidia weaken the gut wall, and bacteria may pass through. In short, feeding dairy products or probiotics will not stop the coccidia through competitive exclusion but does provide nutrients or beneficial bacteria that are useful in any situation.
Producers sometimes give diatomaceous earth (DE) to the birds in the belief that the sharp edges of the fossilized diatoms will damage the parasites and reduce coccidiosis; however, there is no scientific data to support its use...."
ETA: Ammonia also kills oocytes ( make your your birds are WELL away as it must be a high concentration and alow time for for the gas to dissapate afterwards (this is why I have multiple coops at opposite ends of my yard)