It wasn't the best situation that I had to move the peachicks out to the grow out pen before the normal recommend twelve weeks to be sure that they had developed their immune system but that is what I had to do. The oldest was twelve weeks and the youngest was six or seven weeks. Knowing that I have had problems with Coccidiosis in the past I decided to start them on a medicating routine that would include a rotation of Safeguard, Corid, Safeguard, and Corid. I also did an Ivermec pour on for lice because of the close proximity of chickens to the pen. After the rotation of treatments, every one starting on a Monday, I started seeing the classic respiratory problems with the swelling of the eyes, runny noses, coughing, and sneezing so I started a round of oxytetrocycline (sp). Late in that week we were observing the flock of chicks when one that I was concerned about but did not show respiratory symptoms let out a poo that was OMG! bloody squirts! I gathered him up with my precious SweePea, collected stool samples from both of them and took the samples to the vet for a fecal examination. The vet said that she had never seen so much cocci in an exam before. After much discussion she determined that our problem must be the water hardness. Now I don't fully understand the how and why but what I took away from the discussion is that the high level of sulphites in the water changes the chemical composition of the drug making it useless. So, what to do? Yes there is another drug that is off label but I want to treat the birds TODAY. Well since the vet told me to quit fermenting their feed I had been making a wet mash for them morning and evening, they absolutely love it! Solution; put the Corid in the wet mash! With the help of Casportpony we figured out the weight of the birds, both chicks and adults and did the math on how much to put into the mash. Lucky for me I had been feeding them the mash and know how much to make up so it's all easy peasy. I have got to say that with all I have been through with the sickness and trying to figure out why all the different meds were not working for me that this really is a relief to know not only why they were not working but how to administer the meds when needed. Oh, and the hard water? We now use the filtered water from the house. Thanks Kathy, you as always were a great help!