Keep a very close eye on them, females can (ime will) become very territorial and aggressive with each other when they mature. Odds are you will need two separate cages. I don't know if they get along better if they are spayed or not.
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Most people advise to separate rabbits at 3-4 months. They are able to reproduce at 3 months, but it is very, very highly recommended that you wait until at least six months, eight months for the giants.