I have seen an article about sand in the run. It drains quickly and therefore dries fast so less issues with sanitation and smell. Easy for chickens to scratch through it for what they want, but also easy to rake up anything you don't want in there. I saw somewhere some one (The Chicken Chick I think) say that they take a rototiller to their coop and then reapply fresh sand when it needs a good deep clean. I liked the idea.
A rototiller sounds like a good idea once in awhile. When I rake mine out I noticed I'm loosing quite a bit of dirt. We rake the coop out about every 2 or 3 weeks. They free range a ton in our yard so it doesn't get too bad. A 50lb bag of kids sand is about $5 so if I throw some down I don't think it would hurt? Maybe add some DE? I'm a new chicken owner but this site has helped a ton. I'm always reading new things.
I use sand on the floor of my coop run. I spot clean as needed, and rake it up. However, my run is covered, which helps keep the sand drier during the wetter months. (Wet sand is not very effective). Even a tarp over the top can help keep the run dry.
So far, after a year, I haven't needed to rototill it.
It works very well, and dries out the poop quickly.
You want to go about 4-6 inches deep.
If you do use sand, make sure it is 'Masonry' or 'Construction' sand (different particle sizes so it doesn't pack down as much).