Depending on your available space, you could try moving / building a new run on a different side and painting the coop inside and out. Or trying a completely different area of your property. If you're on a well, you might look into having your water tested for pathogens.
@BarnyardChaos now you made me curious! Would soil with natural limestone be more resistant to parasites?
@BarnyardChaos now you made me curious! Would soil with natural limestone be more resistant to parasites?