Yes, it probably will. It did for one I had to isolate for a few weeks, even though she remained in sight and sound of the flock, separated only by chicken wire. Another one only required isolation for the better part of a day before the wound was no longer visibly bloody (with the help of BluKote) and in that case it didn't seem to matter.
When a bully hen is isolated to alter her behavior, it is usually recommended to isolate her for a week, so that by then she is at the bottom of the pecking order.
If there is any way you can get her back sooner, the reintroduction should be easier on her. I do understand this depends on how extensive the wound is, of course.
Good luck.
