Marek's is a very sad problem. From discovery in 1905 until now, there is no cure. Chickens are better off with the vaccine BUT only for the chick to survive the exposure to another chicken that has the virus. The vaccine only prevents the tumors from forming. It does not give them Marek's, cure Marek's, prevent them from being a carrier and passing it on. The chick that gets the vaccine and is quarantined for 3 or more weeks is the lucky one who will live. That's it.
The negatives are it's a leaky vaccine meaning it prevents tumors but does not prevent being a carrier or being exposed. If one would have a whole flock of vaccinated chickens, how would one really know if their chickens are exposed? Unfortunately backyarders do not usually practice chicken keeping that does not put their birds at risk. Namely all in all out-and not mixing new chickens into a flock.
If I had hatched all my chickens or bought strickly hatchery chicks, I would call that a closed flock and one that may not need vaccination. If I continue to add adults or chicks from other places, I run the risk of losing many chickens to Marek's. And Marek's virus in the chicken dander can live on a property for years.
Whether vaccinated or not, and exposed, the other evil is that their immune system will not be hardy. Example, they can get cocci overload at any time. Or, carry a larger amount of bacteria or cocci than normal and their body gets used to it, so the chicken becomes less thrifty.