@Perris this was in our news today (
translated from levende have with google):
ZOOs ARE ALLOWED TO VACCINATE AGAINST BIRD FLU; HOBBY POULTRY FARMERS NOT YET
17 MARCH 2023 - 11:06
Zoos with a vaccination plan against bird flu are allowed to vaccinate. The precondition is that they are affiliated with the Dutch Association of Zoos. Hobby poultry farmers have to wait until implementation bottlenecks have been resolved.
This is what Agriculture Minister Adema writes in a letter to the House of Representatives about the results of the research into vaccines. The vaccines that have passed the test successfully can only be used in chickens for the time being.
The bottlenecks that Adema refers to are the very strict requirements set by the European Commission for vaccination against bird flu. For example, a member state that is going to vaccinate must set up a so-called ''surveillance programme'', which involves high costs. Such a program means that the vaccinated poultry is regularly examined for the presence of virus.
Field trial with two vaccines
Adema is also waiting for the first results of a field trial that will be carried out with two vaccines (HVT-H5 from Ceva Sante Animale and from Boehringer Ingelheim Animal Health). The tests in the laboratory with two so-called ''vector vaccines'' have gone well. They proved sufficiently effective in preventing virus transmission. The field trial can start after the summer, Adema announced. ''The trial itself will last more than a year, among other things to get an idea of how long chickens are still immune after vaccination. The results will come during the course of the field trial. I hope to get the first results on effectiveness before the end of this year. Data on the duration of immunity will become available in 2024 and 2025."
40% mortality despite vaccination with Nobilis vaccine
This could mean that hobby chickens - if all goes well - can be vaccinated at the end of this year, early next year. Around the coming summer, Adema expects the results of further research into the consequences of vaccination with vaccines that prevent the virus from spreading less effectively under field conditions. It is not expected that hobby poultry can be vaccinated with MSD's Nobilis vaccine, which is already registered in the Netherlands. This vaccine has been included in tests conducted so far. After administration of the Nobilis vaccine, 40% mortality of the infected animals and 30% mortality of the contact animals was seen, according to the study. Both HVT-H5 vaccines were found to be 100% effective in reducing morbidity and mortality after infection with the HPAI H5N1 virus. However, vaccination with Nobilis stopped the excretion of virus. ''After vaccination with MSD's Nobilis vaccine, the amount of virus shedding was significantly less than that of the unvaccinated control group. So despite the fact that the antigenic distance of the Nobilis vaccine to the current HPAI H5 clade 2.3.4.4b virus is relatively large, the vaccine was also partly effective for this aspect.''
Pilot on poultry farms
The commercial poultry industry will have to wait for the results of the field trial with the two selected HVT-H5 vaccines and the authorization of the vaccines on the European market. That is the responsibility of the pharmaceutical companies. Adema will prepare a vaccination program that can be implemented on a larger scale in the Netherlands. He indicates that he wants to do this step by step, starting with a pilot at several companies. Many things still need to be sorted out and settled. “It is not only about matters related to the vaccines, but also about the organization and implementation of a vaccination program, in which we carry out the pilot in accordance with the new European regulation,” says Adema. He wants the pilot to start at the end of this year.