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Yes it can, especially if you are in the beginning of a breeding program where you have to raise a number of birds to try and find enough top notch ones to breed from. As the breeding seasons pass you don't have to raise as many to find the good ones and you are more in tune as to what to cull for early.
That is why when a successful breeder of 20 years charges what you consider an outrageous amount for his stock; you just smile -say thank you for allowing me to buy your birds, hand over the money and think about all the years of breeding you have saved.
It is also why when you see a beginner with 10 varieties of 5 different breeds you know they will not be successful.
Having said all that. You always try to cull as early as you can. Study your birds daily and try to find faults. White feathers, eye color, size, wry tail, crooked toes, any abnormalities to your breed or variety. Get rid of them as soon as possible so that the ones that show promise can have more room and attention. Rarely will these cull birds pan out.
Then when they are about 3-4 months old you can start culling for type and color. I raise Modern Game so at this time if they don't have good leg length or do have real long backs I start to cull. I will separate these into what I call my cull pens. They are for sale or give away, but I will keep my eye on them and see if I made any mistakes. I have been known to pull a bird out of the sale area.
After my initial cull I will go into my growing pens every 3 or 4 weeks and do my best to cull half of the birds in it. There may be 30+ birds in that pen, I will try to cull at least 15. IT IS NOT EASY! But I make my choices and then TRY to live with them.
Remember that females mature quicker than males so give the males a lot longer time to mature before making your final choice. In my male lines (BB Red Modern) I always keep 4 or 5 promising cockerels to see how they finish out as Cocks. I almost always breed to cock birds anyway, and you would be surprised how much better a male is as a cock. But then this is in Moderns.
One last thing and then I will leave y'all alone. There is another old saying- If you want to breed something out of your birds, Keep it out of your breeding pens
Bob