Study on Ivermectin residual in eggs, links

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Your customers will have to be exceptionally sensitive `sentinels'.

Off-label ruminant assays: http://www.farad.org/publications/digests/092000ExtralabelIvermectinMoxidectin.pdf

Canadian expertise:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914318/

Thirty days should be more than enough, for IVERMECTIN (shouldn't be using, anyway).

Cattle pour-on is EPRINOMECTIN : http://us.merial.com/producers/cow_calf/products/cowcalf_ivomec_eprinex.asp With ZERO withdrawl times for meat/milk.

From: http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/191504.htm

Ivermectin and doramectin are excreted in milk and are not recommended when milk is intended for human consumption; commensurate with their long period of activity, they have significant withholding periods before slaughter (eg, 35 days), which vary with the formulations (and local regulations). Moxidectin has a relatively low mammalian toxicity, and residual concentrations in milk after topical administration are below threshhold limits resulting in no withholding period in many countries. The chemical structure of the macrocyclic lactone molecule can be manipulated to change the milk partitioning coefficients in lactating dairy animals. This led to the development of eprinomectin, of which only 0.1% of the total dose is eliminated in the milk, resulting in no withholding period for milk worldwide.
Click to expand...

Here is a handy withdrawl chart for approved meds: http://www.cfo.on.ca/_pdfs/PoultryWithdrawalTimeChart-Mar30-07.pdf
 
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Thanks very miuch for the thorough information, and for clarifying to me the more appropriate 'mectin' to use. The most sensitive person I know is my mother-in-law, so I keep her in mind as a bellweather (or potential bellweather). If there's a negative effect to be had from a medication, dye, or perfume she'll have it. I've been doubful in the past about her sensitivity, but a series of 'events' have begun to convince me.

I have access to a wide variety of scientific journals, so when I have the chance I'll dig around to see if anyone has reported specifically on eprinomectin distribution in poultry. Again, thanks very much!
 
Yes, I now use Eprinex rather than Ivomectin. They both kill exactly the same things, why not use the one with zero withdrawl time is my thought. But then Valbazen is what Dawg recommends so I'll be getting that one next go round. I probably don't worm often enough but they're healthy so I figure once or twice a year is doing the trick in my situation.
 
When using Ivermectin/ Ivermectin Plus (the injectable type) you should mix it with Propylene Glycol at the rate of 10 parts Prpylene glycol to 1 part Ivermectin and and each Large Fowl Bird would receive 1cc orally.

I use Fenbendazole (Safeguard) that is for goats mixed at the rate of 9 parts Fenbendazole to 1 part water and each large fowl bird will receive 1 cc orally then 10 days latter they get hit with Ivermectin as described above.


Chris
 
Chemguy wrote: I have access to a wide variety of scientific journals, so when I have the chance I'll dig around to see if anyone has reported specifically on eprinomectin distribution in poultry.
Click to expand...

Try a more generalized search of the class, i.e., `Avermectin'.

Interesting abstract of study on `tagged' Avermectin derivative in suggesting difference in `clearing' between mammals and avians (some Leghorns): http://www.ncbi.nlm.nih.gov/pubmed/9698294
(click on full text/pdf link top right of page for article as it appeared in DM&D).

Also, one can sometimes find good stuff in the bibliographies of research funded by the FAO of the UN (ag/poultry in `low tech' environments):
(Neem oil traps for mites, for instance). http://www.fao.org/

The lack of scientific literacy, combined with the ability to detect at nanogram/picogram amounts and less money/motivation to associate these results with actual risk will lead to interesting consequences: http://www.epa.gov/ppcp/ ...
 
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