Most chickens around 5 pounds would get 250 mg twice a day, so I would mix a capsule in a little cream cheese or egg and give half in the morning and half in the evening. Some posts say 125 mg twice a day. I believe you can be safe with 125-250mg twice a day though. Others say to give 57 mg per pound twice a day, but that is pretty close to 250 mg. Amoxicillin is best for wounds, bumblefoot, enteritis, or for egg yolk peritonitis. Respiratory diseases from bacteria are better treated with tylosin, tiagard/Denagard, or oxytetracycline.