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YES. However, that will only work with a really tiny tube - you could use a feeding tube or similar. Trust me, I have tried. That hole also sits right above a solid piece of plastic; running a tube straight down will get you nowhere. Regular aquarium tubing would be impossible, but you could definitely set up a system using a feeding tube that goes through the hole, down, takes a turn to get through the plastic grille and ends up in the wells or on a sponge.