Here's some info I found:
Efficacy of eprinomectin versus ivermectin for the treatment of chorioptic mange in alpacas
BRISTOL/UNITED KINGDOM
May 30th (MedCon) Four weekly topical administrations of eprinomectin at a dose rate of 500 ìg/kg of body weight proved highly effective at reducing the Chorioptes mite burden in alpacas, scientists report. In two studies Dr. G. L. DAlterio and colleagues from the School of Clinical Veterinary Science, University of Bristol, Langford House, Langford, determined the efficacy of eprinomectin versus ivermectin (study 1), and the field efficacy of eprinomectin (study 2). Study 1 they performed as a single-centre, randomised, treatment-controlled, blinded field trial, study 2 as a single-centre, open, uncontrolled field trial. They are further described in Veterinary Parasitology. In Study 1 the scientists randomly allocated 30 alpacas, all positive for Chorioptes sp. mite, randomly to two treatment groups. Group A received a single topical administration of a 0.5 percent formulation of eprinomectin at the dose rate of 500 ìg/kg. Group B received three subcutaneous administrations at 14 days interval of a one percent formulation of ivermectin at the dose rate of 400 ìg/kg. Response to treatment was assessed by periodic mite count, and skin lesions scored. In Study 2, one group of 19 alpacas received four administrations at weekly interval of topical eprinomectin at the dose rate of 500 ìg/kg, and response to treatment was monitored by mite counts. No localised or systemic side effects were observed in either trial, the scientists report. As a result, there was a statistically significant decrease in mite counts on day seven (p < 0.001) within treatment Groups A and B of Study 1, but mite counts increased again on day 14 and remained high for the duration of the trial in both treatment groups. On day 14 of Study 2, there was a statistically significant reduction in mite counts (p < 0.008) and the mite counts remained very low throughout the remainder of the study. The eprinomectin protocol employed in Study 2, consisting of four weekly topical administrations at the dose rate of 500 ìg/kg of body weight, proved highly effective at reducing the Chorioptes mite burden in alpacas, the scientists concluded. Veterinary
