- Sign: Eggs candle clear; broken out eggs show blood ring or small embryo that died before 3 days of incubation; no dark eye visible. Causes:
- Eggs stored too long or under improper temperature.
- Fumigation improper -- too severe or done between 12 and 96 h of incubation.
- High temperature in early incubation.
- Low temperature in early incubation.
- Eggs damaged during transport by jarring, etc.
- Breeder flock diseases.
- Old breeders.
- Embryological development accidents.
- Inbreeding, chromosome abnormalities.
- Severe nutritional deficiencies, e.g., biotin, vitamin A, copper, vitamin E, boron, or pantothenic acid.
- Frequently associated with a high incidence of infertility.
- Drugs, toxins, or pesticides.
- Contamination.
- Embryos less developed at oviposition, i.e., pre-endoderm or very early endoderm formation.
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