Okay. I found an interesting to-the-point article by UC Davis. Then I looked at my necropsy report , took the words, and looked up the meanings. It's good you brought it up.
What is really interesting is that with all this evidence, I had a Negative pcr for Marek's!!!!! Even with all these findings.
re: UC Davis
Poultry
Marek’s Disease (MD) is a common, acute or chronic, very contagious, and economically
important disease of poultry, caused by an alpha herpes virus, named Marek’s disease virus
(MDV). There is wide variation in pathogenicity
among the strains of MDV, which range from nonpathogenic
to very virulent. MD has been reported
in turkeys, quail and pheasants; however,
chickens of any age are by far the most susceptible
species. MD is the most common disease diagnosed
in California backyard chicken flocks.
MD infection occurs by inhalation of feather and
dander epithelial cells containing infectious virus.
Common clinical conditions include lymphomas
(lymphoid tumors) in multiple internal organs,
peripheral nerves, feather follicles, and eyes; immunosuppression;
transient paralysis; lymphoid
tissue degeneration; and vascular syndromes. Microscopic lesions due to MD can be seen as
early as 2 weeks of age. As a result of MD, flocks may have reduced weight gain, egg production
and feed conversion; and increased susceptibility to other pathogens. Other problems include
increased mortality in layers, and increased condemnation rate in broilers, which can be
as high as 60% and 10% respectively in unvaccinated flocks. Histopathological examination of
affected organs, including peripheral nerves, is very useful for diagnosing MD. Since 1970,
MD has been controlled very successfully through vaccination which can provide greater
than 90% protection if done properly. Interestingly, MD vaccine protects birds only from
tumor formation, not from infection. MD was the first cancer that was successfully controlled
through vaccination in any species, one of the most remarkable achievements of veterinary
medicine. MD vaccination in commercial poultry is performed mostly by in ovo injection at the
19th day of embryo development, but can also be controlled successfully with subcutaneous
vaccination in the neck of day-old chicks.
My findings in my necropsy report: Negative Marek's. Positive Aspergillosis
Pulmonary neoplasia or granuloma :
metastasis/cancer
Aspergillosis: Fungal balls. Mass in lungs(?)
Lymphoreticular hyperplasia and/or spleen lesions
cause by Marek's, tumors (?)
Intralesional hepatonecrosis:
Dying liver tissue between lesions on liver
Sapropytic fungi:
Grows on dead organic matter or dead animals or poop
Lesions are damaged skin
Neoplasms are tumors or abnormal growths
chicken fat fibrin mass in heart -
Jaundice in mucosa/mouth/trach, and in dermis (under epidermis)-system shut down
Some of this seems opportunistic due to low immune system or dying.
Some of this just describes Marek's , I think, to a T, but a Negative pcr??? Does anyone notice these things and question it?
Maybe someone can explain this discrepancy better? I know that Nambroth had some discrepancies as well.
I hope I made this easier to understand.
If you read Nambroth's BIG Marek's FAQ, link at bottom of my page, Nambroth's, Casportpony's and Eggcessive's , you can also see that Marek's can have a large variety of symptoms and those symptoms may be the same in several different illnesses. A flock history can help clarify. But nothing here is an "always".
ood thing I liked him ;-) Pseudomonas in dogs is very difficult to get rid of. I hope chickens are easier.
